Floresta e Ambiente
Floresta e Ambiente
Original Article Wood Science and Technology

Phytochemical Constituents Isolated from the Stem Bark of Bauhinia monandra

Jailton Ferrari; Djalma Menezes de Oliveira; Nadia Machado Aragão

Downloads: 0
Views: 67


ABSTRACT: The methanolic extract from stem bark of Bauhinia monandra, a medicinal plant employed in folk medicine, yielded by column chromatography lup-20(29)-en-3β,24-diol ( 1) and methyl galloate (2) along with β-sitosterol ( 3). These known phytoconstituents are being reported for the first time from this plant and their structures were established by NMR and MS spectral studies and by comparison with their literature data. Furthermore, lup-20(29)-en-3β,24-diol (1 ), a minor constituent, was isolated from this genus for the first time.


phytoconstituents, Leguminosae, methanolic extract


Aderogba MA, Ogundaini AO, Eloff JN. Isolation of two flavonoids from Bauhinia Monandra (KURZ) leaves and their antioxidative effects. African Journal of Traditional, Complementary, and Alternative Medicines 2006; 3(4): 59-65. http://dx.doi.org/10.4314/ajtcam.v3i4.31177.

Agbugui M, Oniye SJ, Auta J. Effects of processing on the mineral content, proximate composition and phytochemical factors of the seeds of bauhinia monandra (kurz). Bayero Journal of Pure and Applied Sciences 2010; 3(1): 23. http://dx.doi.org/10.4314/bajopas.v3i1.58558.

Alade GO, Adebajo AC, Omobuwajo OR, Proksch P, Verspohl EJ. Quercetin, a minor constituent of the antihyperglycemic fraction of Bauhinia monandra leaf. Journal of Diabetes 2012; 4(4): 439-441. http://dx.doi.org/10.1111/j.1753-0407.2012.00222.x. PMid:22742491.

Almeida ER, Guedes MC, Albuquerque JF, Xavier H. Hypoglycemic effect of Bauhinia cheilandra in rats. Fitoterapia 2006; 77(4): 276-278. http://dx.doi.org/10.1016/j.fitote.2006.03.001. PMid:16713131.

Anhwang BA, Ajibola VO, Oniye SJ. Composition of bulk, trace and some rare earth elements in the seeds of Moringa oleifera (Lam) Detarium microcarpum (Guill and Perr) and Bauhinia monandra (Kurz). Journal of Food Technology 2005; 3(3): 290-293.

Aragão PCA, Toledo JB, Morais AA, Braz-Filho R. Substâncias naturais isoladas de Stigmaphyllon tormentosum e Byrsonima variabilis . Química Nova 1990; 13(4): 254-259.

Argolo AC, Sant’Ana AE, Pletsch M, Coelho LC. Antioxidant activity of leaf extracts from Bauhinia monandra. Bioresource Technology 2004; 95(2): 229-233. http://dx.doi.org/10.1016/j.biortech.2003.12.014. PMid:15246449.

Balogun A, Fetuga BL. Fatty acid composition of seed oils of some members of the leguminosae family. Food Chemistry 1985; 17(3): 175-182. http://dx.doi.org/10.1016/0308-8146(85)90066-4.

Boonphong S, Puangsombat P, Baramee A, Mahidol C, Ruchirawat S, Kittakoop P. Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities. Journal of Natural Products 2007; 70(5): 795-801. http://dx.doi.org/10.1021/np070010e. PMid:17480099.

Cechinel-Filho V. Chemical composition and biological potential of plants from the genus Bauhinia. Phytotherapy Research 2009; 23(10): 1347-1354. http://dx.doi.org/10.1002/ptr.2756. PMid:19170142.

Estrada O, Hasegawa M, Gonzalez-Mujíca F, Motta N, Perdomo E, Solorzano A et al. Evaluation of flavonoids from Bauhinia megalandra leaves as inhibitors of glucose-6-phosphatase system. Phytotherapy Research 2005; 19(10): 859-863. http://dx.doi.org/10.1002/ptr.1703. PMid:16261515.

Frankish N, de Sousa-Menezes F, Mills C, Sheridan H. Enhancement of insulin release from the beta-cell line INS-1 by an ethanolic extract of Bauhinia variegata and its major constituent roseoside. Planta Medica 2010; 76(10): 995-997. http://dx.doi.org/10.1055/s-0029-1240868. PMid:20143296.

Fuentes O, Arancibia-Avila P, Alarcón J. Hypoglycemic activity of Bauhinia candicans in diabetic induced rabbits. Fitoterapia 2004; 75(6): 527-532. http://dx.doi.org/10.1016/j.fitote.2004.03.013. PMid:15351105.

Hisham DMN, Lip JM, Noh JM, Normah A, Nabilah MFN. Identification and isolation of methyl gallate as a polar chemical marker for Labisia pumila Benth. Journal of Tropical Agriculture and Food Science 2011; 39(2): 279-284.

Ilkiu-Borges F, Mendonça MS. Morfo-anatomia da semente de Bauhinia monandra Kurz: (Leguminosae-caesalpinioideae). Revista Brasileira de Sementes 2009; 31(4): 168-174. http://dx.doi.org/10.1590/S0101-31222009000400020.

Macêdo MFS, Sisenando HAAACN, Queiroz JDF, Argolo ACC, Saturnino ACRD, Coelho LCBB et al. Determining the genotoxicity of an aqueous infusion of Bauhinia monandra leaves. Revista Brasileira de Farmacognosia 2008; 18(4): 509-516. http://dx.doi.org/10.1590/S0102-695X2008000400002.

Mendes BG, Machado MJ, Falkenberg M. Triagem de glicolipídios em plantas medicinais. Revista Brasileira de Farmacognosia 2006; 16(4): 528. http://dx.doi.org/10.1590/S0102-695X2006000400022.

Menezes FS, Minto ABM, Ruela HS, Kuster M, Sheridan H, Frankish N. Hypoglycemic activity of two Brazilian Bauhinia species: Bauhinia forficata L. and Bauhinia monandra Kurz. Revista Brasileira de Farmacognosia 2007; 17(1): 8-13. http://dx.doi.org/10.1590/S0102-695X2007000100003.

Santos PM, Almeida PDO, Lima ES, Moraes MO, Costa PM, Meira AS et al. Perfil de flavonoides e avaliação do potencial antioxidante e citotóxico de Bauhinia purpurea (Fabaceae) da região amazônica. Química Nova 2014; 37(1): 89-94. http://dx.doi.org/10.1590/S0100-40422014000100017.

Shang XY, Li S, Wang YH, Wang SJ, Yang YC, Shi JG. Chemical constituents of Bauhinia aurea. Zhongguo Zhongyao Zazhi 2006; 31(23): 1953-1955. PMid:17348187.

Silva KL, Cechinel-Filho V. Plantas do gênero Bauhinia: composição química e potencial farmacológico. Química Nova 2002; 25(3): 449-454. http://dx.doi.org/10.1590/S0100-40422002000300018.

Tanaka R, Tabuse M, Matsunaga S. Triterpenes from the stem bark of Phyllanthus flexuosus. Phytochemistry 1988; 27(11): 3563-3567. http://dx.doi.org/10.1016/0031-9422(88)80769-6.

Taweel AMA, Shafae AME, Perveen S, Fawzy GA, Khan SI. Anti-inflammatory and cytotoxic constituents of Bauhinia retusa. International Journal of Pharmacology 2015; 11(4): 372-376. http://dx.doi.org/10.3923/ijp.2015.372.376.

5c13da6e0e88252f4efd3a70 floram Articles
Links & Downloads


Share this page
Page Sections